When this picture first started appearing online, in late 2002, Daschle was serving as Majority leader in the U.S. Senate. Thus he was a highly visible political figure and a natural target for political jokes and smear campaigns. This photo was evidently an attempt to smear him by questioning his intelligence and patriotism. A hoaxer appears to have digitally flipped Daschle's body around along the horizontal axis, reversing his right and left sides (a simple operation using image manipulation software).
Evidence of this horizontal flip: Daschle's jacket is buttoned on the wrong side for a man's jacket. Also, if that is actually his left hand (and not his right hand flipped around) where is his wedding ring?