I watch this Monster Quest show .. I think its on Discovery or Sci Fi Channel.. one of those.
There was one episode about a bigfoot that had attacked a cabin in the woods several times so the owner had placed Boards with upward facing nails to deter further attacks. The bigfoot apparently stepped on one of these boards and left behind blood and tissue evidence.
When tested in the laboratory the results were no direct match to any known species, although they were said to be similar to that of primates.
It was intruguing stuff, Im not sure how easily DNA evidence would be to fake… Im guessing they could have gotten samples from different animals mixed it together and smeared it on the nails… but Im not sure if that would work.
Could be real… but you’d think they would have found all large animals to be found in the USA.